A common and relatively milder derivative of the opiate family, this narcotic is often combined with codeine or other pain relievers and taken by mouth. Codeine is available by prescription only and is found in common cold and cough remedies as narcotics, in addition to blocking pain, are very effective cough suppressants. Other forms of codeine are also available for injection or by suppository. The usual precautions apply, as with any narcotic, and there is a potential for addiction. Constipation can also be a problem, so laxatives are often prescribed along with codeine in order to prevent constipation. Sedation is also an issue and patients should not drive or operate machinery while under the influence of codeine or other narcotics. Certain people are allergic to codeine and may develop itchiness and rashes. In these cases, codeine should be avoided as more serious allergic reactions, even life-threatening anaphylaxis, may occur with further usage.